Super Mario Run is developed in the Unity of Nintendo

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Unity Technologies and Nintendo announced that the upcoming smartphone Mario game the Super Mario Run is in development with the Unity engine the Unity of Nintendo.
The new Super Mario Run release in 2016 December on iOS and later on Android also as a new one finger operation Mario game.

As you can see with the Unity engine you can develop even high-end games not just indie titles if you want. More information about the Super Mario Run comes later.